Synthesis of 6H-indolo[2,3-b]quinoxaline-N-glycosides and their cytotoxic activity against human ceratinocytes (HaCaT).

نویسندگان

  • Katrin Marie Driller
  • Stefanie Libnow
  • Martin Hein
  • Manuela Harms
  • Kristian Wende
  • Michael Lalk
  • Dirk Michalik
  • Helmut Reinke
  • Peter Langer
چکیده

N-glycosides of 6H-indolo[2,3-b]quinoxalines were prepared and structurally characterized. The synthesis relies on the cyclocondensation of isatine-N-glycosides with 1,2-diaminobenzenes. Some products exhibit weak cytotoxic activity against human ceratinocytes (HaCaT).

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 6 22  شماره 

صفحات  -

تاریخ انتشار 2008